When was mono discovered

New strategy discovered toward possible prevention of cancers tied to mono. Retrieved November 12, from www. In a new paper, researchers connect the onset and severity of mono to ScienceDaily shares links with sites in the TrendMD network and earns revenue from third-party advertisers, where indicated.

Print Email Share. Boy or Girl? Just a Game? The program has a research partnership with the Uganda Cancer Institute and research ties in China.

About 10 percent of gastric cancers and almost percent of nasopharyngeal carcinomas — a type of head and neck cancer — are linked to EBV.

Treating the tumors, which grow deep inside the nasopharynx the upper part of the throat, behind the nose requires intensive radiation and often chemotherapy. In China, a vaccine would make an enormous difference. Previously, scientists had identified a small number of antibodies to EBV, but they all came from EBV-infected mice, not humans. The mouse antibody that best blocks infection targets a molecule on the surface of EBV called glycoprotein , or gp, which helps the virus attach to B cells, a type of immune cell that is infected by EBV.

Although the only human clinical trial of an experimental gptargeted EBV vaccine conducted to date showed a clinical benefit — fewer people developed infectious mononucleosis — the vaccine did not prevent EBV infection itself. Drawing on what has been learned from research on the immune response in people infected with HIV, McGuire and his team searched for and found antibodies to EBV in the blood serum of infected humans.

McGuire just started his own lab last July, after moving from postdoc to an assistant faculty appointment, but he began this work under a VIDD Faculty Initiative Grant awarded in David Veesler and Hutch researcher Dr.

Marie Pancera — who recently co-authored a paper on a new malaria antibody and its target — they were able to describe the structure of the binding site soon afterward. The next step will be testing the antibody in an animal model; McGuire is applying for funding for that project now. Besides holding out promise for a vaccine, which would work by teaching the body to make such an antibody, another potential use of these results would be to directly administer the antibody intravenously, as is now being tested for an antibody against HIV in a global clinical trial called the AMP Study , short for "antibody-mediated protection.

And down the road, there is the possibility that lessons learned from finding antibodies for HIV, malaria and now EBV could be applied to additional viruses. Join the conversation about EBV on our Facebook page. Previously, she covered medicine and health policy for the Los Angeles Times, where she was part of a team that won a Pulitzer Prize for Public Service. Furthermore the atypical manifestation of glandular fever could be identified. In recent years the problems of persistent and chronic infections were discussed.

At last the antiviral chemotherapy was tested. Abstract Glandular fever was described by Emil Pfeiffer in